首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   2568662篇
  免费   189287篇
  国内免费   7538篇
耳鼻咽喉   34296篇
儿科学   84951篇
妇产科学   71574篇
基础医学   360883篇
口腔科学   69590篇
临床医学   232956篇
内科学   511343篇
皮肤病学   62437篇
神经病学   212034篇
特种医学   99826篇
外国民族医学   736篇
外科学   385539篇
综合类   50236篇
现状与发展   5篇
一般理论   967篇
预防医学   194439篇
眼科学   56485篇
药学   187510篇
  8篇
中国医学   5154篇
肿瘤学   144518篇
  2019年   20636篇
  2018年   29318篇
  2017年   22624篇
  2016年   26282篇
  2015年   29545篇
  2014年   40484篇
  2013年   60483篇
  2012年   80351篇
  2011年   84624篇
  2010年   51079篇
  2009年   49202篇
  2008年   79154篇
  2007年   83957篇
  2006年   85708篇
  2005年   81865篇
  2004年   78835篇
  2003年   75965篇
  2002年   73214篇
  2001年   128242篇
  2000年   131044篇
  1999年   109826篇
  1998年   29639篇
  1997年   26209篇
  1996年   26439篇
  1995年   27243篇
  1994年   24941篇
  1993年   23300篇
  1992年   85100篇
  1991年   81577篇
  1990年   78779篇
  1989年   76037篇
  1988年   69435篇
  1987年   67987篇
  1986年   63528篇
  1985年   60506篇
  1984年   44919篇
  1983年   37865篇
  1982年   22377篇
  1981年   19910篇
  1979年   38906篇
  1978年   27377篇
  1977年   23175篇
  1976年   21425篇
  1975年   22764篇
  1974年   26745篇
  1973年   25344篇
  1972年   23736篇
  1971年   21944篇
  1970年   20163篇
  1969年   19418篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.

Background

Hyperglycaemia is common in patients with acute brain injury admitted to an intensive care unit (ICU). Many studies have found associations between development of hyperglycaemia and increased mortality in hospitalised patients. However, the optimal target for blood glucose control is unknown. We want to conduct a systematic review with meta-analysis and trial sequential analysis to explore the beneficial and harmful effects of restrictive versus liberal glucose control on patient outcomes in adults with severe acute brain injury.

Methods

We will systematically search medical databases including CENTRAL, Embase, MEDLINE and trial registries. We will search the following websites for ongoing or unpublished trials: http://www.controlled-trials.com/ , http://www.clinicaltrials.gov/ , www.eudraCT.com , http://centerwatch.com/ , The Cochrane Library's CENTRAL, PubMed, EMBASE, Science Citation Index Expanded and CINAHL. Two authors will independently review and select trials and extract data. We will include randomised trials comparing levels of glucose control in our analyses and observational studies will be included to address potential harms. The primary outcomes are defined as all-cause mortality, functional outcome and health-related quality of life. Secondary outcomes include serious adverse events including hypoglycaemia, length of ICU stay and duration of mechanical ventilation, and explorative outcomes including intracranial pressure and infection. Trial Sequential Analysis will be used to investigate the risk of type I error due to repetitive testing and to further explore imprecision. Quality of trials will be evaluated using the Cochrane Risk of Bias tool, and quality of evidence will be assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach.

Discussion

The results of the systematic review will be disseminated through peer-reviewed publication. With the review, we hope to inform future randomised clinical trials and improve clinical practice.  相似文献   
12.
Investigational New Drugs - Although many cancer drugs are clinically approved, they still suffer from no adequate efficiency or drug resistance, or bad side effects. Therefore, developing safer...  相似文献   
13.
14.
15.
16.
17.
PurposeThe clinical manifestations of rickettsial diseases mimic other endemic infections with similar presentations thus posing a serious challenge to clinicians for their diagnosis. For the diagnosis of rickettsial disease serological tests like Weil Felix, ELISA and IFA are used. There are limited studies that have evaluated different serological tests for the diagnosis of rickettsial diseases. Therefore, the present study was undertaken to evaluate the ELISA and Weil Felix test for the diagnosis of rickettsial diseases prevalent in this region.MethodsSamples from 281 patients clinically suspected of rickettsial diseases were tested for spotted fever group (SFG), typhus group (TG) and scrub typhus group (STG) by Weil Felix, ELISA and IFA was taken as the gold standard. Baseline titers and cut-off ODs were calculated by taking samples from healthy blood donors.ResultsThe sensitivity, specificity, positive and negative predictive value of Weil Felix test ranged from 30% to 44%, 83.46%–97.86%, 9%–77%, 92–96% respectively. The sensitivity and specificity, positive and negative predictive value of ELISA ranged from 80.77% to 96.15%, 96.33%–98.43%, 70.21%–88.64%, 92.89%–99.60% respectively. Maximum cross-reactions were observed between SFG and STG by the Weil Felix test and between STG and TG by ELISA.ConclusionsELISA was found to be sensitive and specific for the diagnosis of rickettsial diseases. It is easy to perform, does not require a technical expert for result interpretation and a large number of samples can be processed at a time.  相似文献   
18.
Bulletin of Experimental Biology and Medicine - The psychopharmacological effects of a stimulator of functions of progenitor cells of the nervous tissue STAT3 inhibitor (STAT3 Inhibitor XIV, LLL12)...  相似文献   
19.
20.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号